Publications

Below is a list of publication associated with SCOR.
  1. Sam S, Vellanki P, Yalamanchi SK, Bergman RN, Dunaif A  Exaggerated glucagon responses to hypoglycemia in women with polycystic ovary syndrome.  Metabolism  2017 Jun;71:125-131. pii:S0026-0495(17)30088-4
  2. Gorsic LK, Kosova G, Werstein B, Sisk R, Legro RS, Hayes MG, Teixeira JM, Dunaif A, Urbanek M  Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome.  J Clin Endocrinol Metab  2017 May 12;. doi:10.1210/jc.2017-00612
  3. Abbott DH, Rayome BH, Dumesic DA, Lewis KC, Edwards AK, Wallen K, Wilson ME, Appt SE, Levine JE  Clustering of PCOS-like traits in naturally hyperandrogenic female rhesus monkeys.  Hum Reprod  2017 Apr 01;32(4):923-936. doi:10.1093/humrep/dex036
  4. Gibson-Helm M, Teede H, Dunaif A, Dokras A  Delayed Diagnosis and a Lack of Information Associated With Dissatisfaction in Women With Polycystic Ovary Syndrome.  J Clin Endocrinol Metab  2017 Feb 01;102(2):604-612. doi:10.1210/jc.2016-2963
  5. Azziz R, Carmina E, Chen Z, Dunaif A, Laven JS, Legro RS, Lizneva D, Natterson-Horowtiz B, Teede HJ, Yildiz BO  Polycystic ovary syndrome.  Nat Rev Dis Primers  2016 08 11;2:16057. doi:10.1038/nrdp.2016.57
  6. Abbott DH, Levine JE, Dumesic DA  Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits.  Curr Pharm Des  2016;22(36):5625-5633
  7. Navarro G, Xu W, Jacobson DA, Wicksteed B, Allard C, Zhang G, De Gendt K, Kim SH, Wu H, Zhang H, Verhoeven G, Katzenellenbogen JA, Mauvais-Jarvis F  Extranuclear Actions of the Androgen Receptor Enhance Glucose-Stimulated Insulin Secretion in the Male.  Cell Metab  2016 May 10;23(5):837-51. doi:10.1016/j.cmet.2016.03.015
  8. Torchen LC, Kumar A, Kalra B, Savjani G, Sisk R, Legro RS, Dunaif A  Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome.  Fertil Steril  2016 Jul;106(1):50-5. doi:10.1016/j.fertnstert.2016.03.029
  9. Torchen LC, Idkowiak J, Fogel NR, O'Neil DM, Shackleton CH, Arlt W, Dunaif A  Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome.  J Clin Endocrinol Metab  2016 May;101(5):2069-75. doi:10.1210/jc.2015-3926
  10. Dunaif A  Perspectives in Polycystic Ovary Syndrome: From Hair to Eternity.  J Clin Endocrinol Metab  2016 Mar;101(3):759-68. doi:10.1210/jc.2015-3780
  11. Hayes MG, Urbanek M, Ehrmann DA, Armstrong LL, Lee JY, Sisk R, Karaderi T, Barber TM, McCarthy MI, Franks S, Lindgren CM, Welt CK, Diamanti-Kandarakis E, Panidis D, Goodarzi MO, Azziz R, Zhang Y, James RG, Olivier M, Kissebah AH, , Stener-Victorin E, Legro RS, Dunaif A  Corrigendum: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.  Nat Commun  2016 Feb 12;7:10762. doi:10.1038/ncomms10762
  12. Dubois SL, Wolfe A, Radovick S, Boehm U, Levine JE  Estradiol Restrains Prepubertal Gonadotropin Secretion in Female Mice via Activation of ERα in Kisspeptin Neurons.  Endocrinology  2016 Apr;157(4):1546-54. doi:10.1210/en.2015-1923
  13. Hayes MG, Urbanek M, Ehrmann DA, Armstrong LL, Lee JY, Sisk R, Karaderi T, Barber TM, McCarthy MI, Franks S, Lindgren CM, Welt CK, Diamanti-Kandarakis E, Panidis D, Goodarzi MO, Azziz R, Zhang Y, James RG, Olivier M, Kissebah AH, , Stener-Victorin E, Legro RS, Dunaif A  Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.  Nat Commun  2015 Aug 18;6:7502. doi:10.1038/ncomms8502
  14. Stevens WW, Peters AT, Suh L, Norton JE, Kern RC, Conley DB, Chandra RK, Tan BK, Grammer LC, Harris KE, Carter RG, Kato A, Urbanek M, Schleimer RP, Hulse KE  A retrospective, cross-sectional study reveals that women with CRSwNP have more severe disease than men.  Immun Inflamm Dis  2015 Mar;3(1):14-22. doi:10.1002/iid3.46
  15. Navarro G, Allard C, Xu W, Mauvais-Jarvis F  The role of androgens in metabolism, obesity, and diabetes in males and females.  Obesity (Silver Spring)  2015 Apr;23(4):713-9. doi:10.1002/oby.21033
  16. Dubois SL, Acosta-Martínez M, DeJoseph MR, Wolfe A, Radovick S, Boehm U, Urban JH, Levine JE  Positive, but not negative feedback actions of estradiol in adult female mice require estrogen receptor α in kisspeptin neurons.  Endocrinology  2015 Mar;156(3):1111-20. doi:10.1210/en.2014-1851
  17. Bethea CL, Reddy AP, Flowers M, Shapiro RA, Colman RJ, Abbott DH, Levine JE  High fat diet decreases beneficial effects of estrogen on serotonin-related gene expression in marmosets.  Prog Neuropsychopharmacol Biol Psychiatry  2015 Apr 03;58:71-80. doi:10.1016/j.pnpbp.2014.11.008
  18. Liu DM, Torchen LC, Sung Y, Paparodis R, Legro RS, Grebe SK, Singh RJ, Taylor RL, Dunaif A  Evidence for gonadotrophin secretory and steroidogenic abnormalities in brothers of women with polycystic ovary syndrome.  Hum Reprod  2014 Dec;29(12):2764-72. doi:10.1093/humrep/deu282
  19. Nicol LE, O'Brien TD, Dumesic DA, Grogan T, Tarantal AF, Abbott DH  Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys.  PLoS One  2014;9(9):e106527. doi:10.1371/journal.pone.0106527
  20. Torchen LC, Fogel NR, Brickman WJ, Paparodis R, Dunaif A  Persistent apparent pancreatic β-cell defects in premenarchal PCOS relatives.  J Clin Endocrinol Metab  2014 Oct;99(10):3855-62. doi:10.1210/jc.2014-1474
  21. Kobaly K, Vellanki P, Sisk RK, Armstrong L, Lee JY, Lee J, Hayes MG, Urbanek M, Legro RS, Dunaif A  Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome.  J Clin Endocrinol Metab  2014 Aug;99(8):2961-6. doi:10.1210/jc.2013-4338
  22. Mauvais-Jarvis F  Developmental androgenization programs metabolic dysfunction in adult mice: Clinical implications.  Adipocyte  2014 Apr 01;3(2):151-4. doi:10.4161/adip.27746
  23. Dumesic DA, Goodarzi MO, Chazenbalk GD, Abbott DH  Intrauterine environment and polycystic ovary syndrome.  Semin Reprod Med  2014 May;32(3):159-65. doi:10.1055/s-0034-1371087
  24. Nohara K, Laque A, Allard C, Münzberg H, Mauvais-Jarvis F  Central mechanisms of adiposity in adult female mice with androgen excess.  Obesity (Silver Spring)  2014 Jun;22(6):1477-84. doi:10.1002/oby.20719
  25. Bernal-Mizrachi E, Kulkarni RN, Scott DK, Mauvais-Jarvis F, Stewart AF, Garcia-Ocaña A  Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map.  Diabetes  2014 Mar;63(3):819-31. doi:10.2337/db13-1146
  26. Bhatt S, Mutharasan P, Garcia OA, Jafari N, Legro RS, Dunaif A, Urbanek M  The inflammatory gene pathway is not a major contributor to polycystic ovary snydrome.  J Clin Endocrinol Metab  2014 Mar;99(3):E567-71. doi:10.1210/jc.2013-2342
  27. Nohara K, Liu S, Meyers MS, Waget A, Ferron M, Karsenty G, Burcelin R, Mauvais-Jarvis F  Developmental androgen excess disrupts reproduction and energy homeostasis in adult male mice.  J Endocrinol  2013 Dec;219(3):259-68. doi:10.1530/JOE-13-0230
  28. Dunaif A, Fauser BC  Renaming PCOS--a two-state solution.  J Clin Endocrinol Metab  2013 Nov;98(11):4325-8. doi:10.1210/jc.2013-2040
  29. Abbott DH, Bacha F  Ontogeny of polycystic ovary syndrome and insulin resistance in utero and early childhood.  Fertil Steril  2013 Jul;100(1):2-11. doi:10.1016/j.fertnstert.2013.05.023
  30. Ackerman CM, Lowe LP, Dyer AR, Hayes MG, Metzger BE, Lowe WL, Urbanek M,   Maternal testosterone levels are associated with C-peptide levels in the Mexican American subset of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study cohort.  Horm Metab Res  2013 Aug;45(8):617-20. doi:10.1055/s-0033-1347262
  31. Nohara K, Waraich RS, Liu S, Ferron M, Waget A, Meyers MS, Karsenty G, Burcelin R, Mauvais-Jarvis F  Developmental androgen excess programs sympathetic tone and adipose tissue dysfunction and predisposes to a cardiometabolic syndrome in female mice.  Am J Physiol Endocrinol Metab  2013 Jun 15;304(12):E1321-30. doi:10.1152/ajpendo.00620.2012
  32. Raja-Khan N, Urbanek M, Rodgers RJ, Legro RS  The role of TGF-β in polycystic ovary syndrome.  Reprod Sci  2014 Jan;21(1):20-31. doi:10.1177/1933719113485294
  33. El Muayed M, Raja MR, Zhang X, MacRenaris KW, Bhatt S, Chen X, Urbanek M, O'Halloran TV, Lowe WL  Accumulation of cadmium in insulin-producing β cells.  Islets  ;4(6):405-16. doi:10.4161/isl.23101
  34. Mauvais-Jarvis F, Clegg DJ, Hevener AL  The role of estrogens in control of energy balance and glucose homeostasis.  Endocr Rev  2013 Jun;34(3):309-38. doi:10.1210/er.2012-1055
  35. Abbott DH, Nicol LE, Levine JE, Xu N, Goodarzi MO, Dumesic DA  Nonhuman primate models of polycystic ovary syndrome.  Mol Cell Endocrinol  2013 Jul 05;373(1-2):21-8. doi:10.1016/j.mce.2013.01.013
  36. Sasidevi A, Vellanki P, Kunselman AR, Raja-Khan N, Dunaif A, Legro RS  Familial aggregation of circulating C-reactive protein in polycystic ovary syndrome.  Hum Reprod  2013 Mar;28(3):770-6. doi:10.1093/humrep/des416
  37. Liu S, Kilic G, Meyers MS, Navarro G, Wang Y, Oberholzer J, Mauvais-Jarvis F  Oestrogens improve human pancreatic islet transplantation in a mouse model of insulin deficient diabetes.  Diabetologia  2013 Feb;56(2):370-81. doi:10.1007/s00125-012-2764-1
  38. Mutharasan P, Galdones E, Peñalver Bernabé B, Garcia OA, Jafari N, Shea LD, Woodruff TK, Legro RS, Dunaif A, Urbanek M  Evidence for chromosome 2p16.3 polycystic ovary syndrome susceptibility locus in affected women of European ancestry.  J Clin Endocrinol Metab  2013 Jan;98(1):E185-90. doi:10.1210/jc.2012-2471
  39. Kosova G, Urbanek M  Genetics of the polycystic ovary syndrome.  Mol Cell Endocrinol  2013 Jul 05;373(1-2):29-38. doi:10.1016/j.mce.2012.10.009
  40. Diamanti-Kandarakis E, Dunaif A  Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications.  Endocr Rev  2012 Dec;33(6):981-1030. doi:10.1210/er.2011-1034
  41. Strauss JF, McAllister JM, Urbanek M  Persistence pays off for PCOS gene prospectors.  J Clin Endocrinol Metab  2012 Jul;97(7):2286-8. doi:10.1210/jc.2012-2109
  42. Witchel SF, Recabarren SE, González F, Diamanti-Kandarakis E, Cheang KI, Duleba AJ, Legro RS, Homburg R, Pasquali R, Lobo RA, Zouboulis CC, Kelestimur F, Fruzzetti F, Futterweit W, Norman RJ, Abbott DH  Emerging concepts about prenatal genesis, aberrant metabolism and treatment paradigms in polycystic ovary syndrome.  Endocrine  2012 Dec;42(3):526-34. doi:10.1007/s12020-012-9701-4
  43. Mauvais-Jarvis F  Estrogen sulfotransferase: intracrinology meets metabolic diseases.  Diabetes  2012 Jun;61(6):1353-4. doi:10.2337/db12-0357
  44. Tiano JP, Mauvais-Jarvis F  Molecular mechanisms of estrogen receptors' suppression of lipogenesis in pancreatic β-cells.  Endocrinology  2012 Jul;153(7):2997-3005. doi:10.1210/en.2011-1980
  45. Tiano J, Mauvais-Jarvis F  Selective estrogen receptor modulation in pancreatic β-cells and the prevention of type 2 diabetes.  Islets  ;4(2):173-6. doi:10.4161/isl.19747
  46. Layden BT, Yalamanchi SK, Wolever TM, Dunaif A, Lowe WL  Negative association of acetate with visceral adipose tissue and insulin levels.  Diabetes Metab Syndr Obes  2012;5:49-55. doi:10.2147/DMSO.S29244
  47. Tiano JP, Mauvais-Jarvis F  Importance of oestrogen receptors to preserve functional β-cell mass in diabetes.  Nat Rev Endocrinol  2012 Feb 14;8(6):342-51. doi:10.1038/nrendo.2011.242
  48. Yalamanchi SK, Sam S, Cardenas MO, Holaday LW, Urbanek M, Dunaif A  Association of fibrillin-3 and transcription factor-7-like 2 gene variants with metabolic phenotypes in PCOS.  Obesity (Silver Spring)  2012 Jun;20(6):1273-8. doi:10.1038/oby.2011.400
  49. Marshall JC, Dunaif A  Should all women with PCOS be treated for insulin resistance?  Fertil Steril  2012 Jan;97(1):18-22. doi:10.1016/j.fertnstert.2011.11.036
  50. Goodarzi MO, Jones MR, Li X, Chua AK, Garcia OA, Chen YD, Krauss RM, Rotter JI, Ankener W, Legro RS, Azziz R, Strauss JF, Dunaif A, Urbanek M  Replication of association of DENND1A and THADA variants with polycystic ovary syndrome in European cohorts.  J Med Genet  2012 Feb;49(2):90-5. doi:10.1136/jmedgenet-2011-100427